NIMBioS Tutorial: Evolutionary Quantitative Genetics 2016

Bookmarked NIMBioS Tutorial: Evolutionary Quantitative Genetics 2016 by NIMBioS (nimbios.org)
This tutorial will review the basics of theory in the field of evolutionary quantitative genetics and its connections to evolution observed at various time scales. Quantitative genetics deals with the inheritance of measurements of traits that are affected by many genes. Quantitative genetic theory for natural populations was developed considerably in the period from 1970 to 1990 and up to the present, and it has been applied to a wide range of phenomena including the evolution of differences between the sexes, sexual preferences, life history traits, plasticity of traits, as well as the evolution of body size and other morphological measurements. Textbooks have not kept pace with these developments, and currently few universities offer courses in this subject aimed at evolutionary biologists. There is a need for evolutionary biologists to understand this field because of the ability to collect large amounts of data by computer, the development of statistical methods for changes of traits on evolutionary trees and for changes in a single species through time, and the realization that quantitative characters will not soon be fully explained by genomics. This tutorial aims to fill this need by reviewing basic aspects of theory and illustrating how that theory can be tested with data, both from single species and with multiple-species phylogenies. Participants will learn to use R, an open-source statistical programming language, to build and test evolutionary models. The intended participants for this tutorial are graduate students, postdocs, and junior faculty members in evolutionary biology.

Network Science by Albert-László Barabási

Bookmarked Network Science by Albert-László BarabásiAlbert-László Barabási (Cambridge University Press)
I ran across a link to this textbook by way of a standing Google alert, and was excited to check it out. I was immediately disappointed to think that I would have to wait another month and change for the physical textbook to be released, but made my pre-order directly. Then with a bit of digging around, I realized that individual chapters are available immediately to quench my thirst until the physical text is printed next month.

The power of network science, the beauty of network visualization.

Network Science, a textbook for network science, is freely available under the Creative Commons licence. Follow its development on Facebook, Twitter or by signing up to our mailing list, so that we can notify you of new chapters and developments.

The book is the result of a collaboration between a number of individuals, shaping everything, from content (Albert-László Barabási), to visualizations and interactive tools (Gabriele Musella, Mauro Martino, Nicole Samay, Kim Albrecht), simulations and data analysis (Márton Pósfai). The printed version of the book will be published by Cambridge University Press in 2016. In the coming months the website will be expanded with an interactive version of the text, datasets, and slides to teach the material.

Book Contents

Personal Introduction
1. Introduction
2. Graph Theory
3. Random Networks
4. The Scale-Free Property
5. The Barabási-Albert Model
6. Evolving Networks
7. Degree Correlations
8. Network Robustness
9. Communities
10. Spreading Phenomena
Usage & Acknowledgements
About

Albert-László Barabási
on Network Science (book website)

Networks are everywhere, from the Internet, to social networks, and the genetic networks that determine our biological existence. Illustrated throughout in full colour, this pioneering textbook, spanning a wide range of topics from physics to computer science, engineering, economics and the social sciences, introduces network science to an interdisciplinary audience. From the origins of the six degrees of separation to explaining why networks are robust to random failures, the author explores how viruses like Ebola and H1N1 spread, and why it is that our friends have more friends than we do. Using numerous real-world examples, this innovatively designed text includes clear delineation between undergraduate and graduate level material. The mathematical formulas and derivations are included within Advanced Topics sections, enabling use at a range of levels. Extensive online resources, including films and software for network analysis, make this a multifaceted companion for anyone with an interest in network science.

Source: Cambridge University Press

The textbook is available for purchase in September 2016 from Cambridge University Press. Pre-order now on Amazon.com.

If you’re not already doing so, you should follow Barabási on Twitter.

Disconnected, Fragmented, or United? A Trans-disciplinary Review of Network Science

Bookmarked Disconnected, Fragmented, or United? A Trans-disciplinary Review of Network Science by César A. HidalgoCésar A. Hidalgo (Applied Network Science | SpringerLink)
Applied Network Science

Abstract

During decades the study of networks has been divided between the efforts of social scientists and natural scientists, two groups of scholars who often do not see eye to eye. In this review I present an effort to mutually translate the work conducted by scholars from both of these academic fronts hoping to continue to unify what has become a diverging body of literature. I argue that social and natural scientists fail to see eye to eye because they have diverging academic goals. Social scientists focus on explaining how context specific social and economic mechanisms drive the structure of networks and on how networks shape social and economic outcomes. By contrast, natural scientists focus primarily on modeling network characteristics that are independent of context, since their focus is to identify universal characteristics of systems instead of context specific mechanisms. In the following pages I discuss the differences between both of these literatures by summarizing the parallel theories advanced to explain link formation and the applications used by scholars in each field to justify their approach to network science. I conclude by providing an outlook on how these literatures can be further unified.

Weekly Recap: Interesting Articles 7/24-7/31 2016

Went on vacation or fell asleep at the internet wheel this week? Here’s some of the interesting stuff you missed.

Science & Math

Publishing

Indieweb, Internet, Identity, Blogging, Social Media

General

Ten Simple Rules for Taking Advantage of Git and GitHub

Bookmarked Ten Simple Rules for Taking Advantage of Git and GitHub (journals.plos.org)
Bioinformatics is a broad discipline in which one common denominator is the need to produce and/or use software that can be applied to biological data in different contexts. To enable and ensure the replicability and traceability of scientific claims, it is essential that the scientific publication, the corresponding datasets, and the data analysis are made publicly available [1,2]. All software used for the analysis should be either carefully documented (e.g., for commercial software) or, better yet, openly shared and directly accessible to others [3,4]. The rise of openly available software and source code alongside concomitant collaborative development is facilitated by the existence of several code repository services such as SourceForge, Bitbucket, GitLab, and GitHub, among others. These resources are also essential for collaborative software projects because they enable the organization and sharing of programming tasks between different remote contributors. Here, we introduce the main features of GitHub, a popular web-based platform that offers a free and integrated environment for hosting the source code, documentation, and project-related web content for open-source projects. GitHub also offers paid plans for private repositories (see Box 1) for individuals and businesses as well as free plans including private repositories for research and educational use.

Design and Control of Self-organizing Systems

Bookmarked Design and Control of Self-organizing Systems by Carlos Gershenson (scifunam.fisica.unam.mx)
UNAM Mexico City has an available free download of Carlos Gershenson’s 2007 text.

Complex systems are usually difficult to design and control. There are several particular methods for coping with complexity, but there is no general approach to build complex systems. In this book I propose a methodology to aid engineers in the design and control of complex systems. This is based on the description of systems as self-organizing. Starting from the agent metaphor, the methodology proposes a conceptual framework and a series of steps to follow to find proper mechanisms that will promote elements to find solutions by actively interacting among themselves.

Design and Control of Self-organizing Systems by Carlos Gershenson (2007)
Design and Control of Self-organizing Systems by Carlos Gershenson (2007)

Penguin Revives Decades-Old Software for 30th Anniversary Edition of “The Blind Watchmaker” | The Digital Reader

Liked Penguin Revives Decades-Old Software for 30th Anniversary Edition of "The Blind Watchmaker" by Nate Hoffelder (The Digital Reader)
Even in 2016, publishers and authors are still struggling when it comes to re-releasing decades-old books, but Penguin had a unique problem when it set out to publish a 30th anniversary edition of Richard Dawkin's The Blind Watchmaker.<br /><br />The Bookseller reports that Penguin decided to revive four programs Dawkins wrote in 1986. Written in Pascal for the Mac, The Watchmaker Suite was an experiment in algorithmic evolution. Users could run the programs and create a biomorph, and then watch it evolve across the generations.<br /><br />And now you can do the same in your web browser.<br /><br />A website, MountImprobable.com, was built by the publisher’s in-house Creative Technology team—comprising community manager Claudia Toia, creative developer Mathieu Triay and cover designer Matthew Young—who resuscitated and redeployed code Dawkins wrote in the 1980s and ’90s to enable users to create unique, “evolutionary” imprints. The images will be used as cover imagery on Dawkins’ trio to grant users an entirely individual, personalised print copy.

A New Thermodynamics Theory of the Origin of Life | Quanta Magazine

Bookmarked A New Physics Theory of Life by Natalie Wolchover (quantamagazine.org)
Jeremy England, a 31-year-old physicist at MIT, thinks he has found the underlying physics driving the origin and evolution of life.
References:

Hypothesis annotations

[ hypothesis user = 'chrisaldrich' tags = 'EnglandQM']

Bits from Brains for Biologically Inspired Computing | Computational Intelligence

Bookmarked Bits from Brains for Biologically Inspired Computing (Frontiers in Robotics and AI | Computational Intelligence journal.frontiersin.org)
Inspiration for artificial biologically inspired computing is often drawn from neural systems. This article shows how to analyze neural systems using information theory with the aim of obtaining constraints that help to identify the algorithms run by neural systems and the information they represent. Algorithms and representations identified this way may then guide the design of biologically inspired computing systems. The material covered includes the necessary introduction to information theory and to the estimation of information-theoretic quantities from neural recordings. We then show how to analyze the information encoded in a system about its environment, and also discuss recent methodological developments on the question of how much information each agent carries about the environment either uniquely or redundantly or synergistically together with others. Last, we introduce the framework of local information dynamics, where information processing is partitioned into component processes of information storage, transfer, and modification – locally in space and time. We close by discussing example applications of these measures to neural data and other complex systems.

My Review Copy of The Big Picture by Sean Carroll

I’m already a major chunk of the way through the book, having had an early ebook version of the text prior to publication. This is the published first edition with all the diagrams which I wanted to have prior to finishing my full review, which is forthcoming.

One thing I will mention is that it’s got quite a bit more philosophy in it than most popular science books with such a physics bent. Those who aren’t already up to speed on the math and science of modern physics can certainly benefit from the book (like most popular science books of its stripe, it doesn’t have any equations — hairy or otherwise), and it’s certain to help many toward becoming members of both of C.P. Snow’s two cultures. It might not be the best place for mathematicians and physicists to start moving toward the humanities with the included philosophy as the philosophy is very light and spotty in places and the explanations of the portions they’re already aware of may put them out a bit.

I’m most interested to see how he views complexity and thinking in the final portion of the text.

More detail to come…

How Can We Apply Physics to Biology?

Bookmarked How Can We Apply Physics to Biology? by Philip Ball (nautil.us)
We don’t yet know quite what a physics of biology will consist of. But we won’t understand life without it.
This is an awesome little article with some interesting thought and philosophy on the current state of physics within biology and other related areas of study. It’s also got some snippets of history which aren’t frequently discussed in longer form texts.

Happy 100th Birthday Claude Shannon

Many regular readers here are sure to know who Claude Shannon is, but sadly most of the rest of the world is in the dark. To give you an idea of his importance in society and even a bit in pop culture, today’s Google doodle celebrates Shannon’s life and work.

Overview of Shannon’s Work

Most importantly, Shannon, in his 1937 Master’s Thesis at Massachusetts Institute of Technology applied George Boole’s algebra (better known now as Boolean Algebra) to electric circuits thereby making the modern digital revolution possible. To give you an idea of how far we’ve come, the typical high school student can now read and understand all of its content. If you’d like to give it a try, you can download it from MIT’s website.

His other huge accomplishment was a journal article he wrote in 1948 entitled “A Mathematical Theory of Communication” in the Bell Labs Journal. When it was republished a year later, one of the most notable changes was in the new title “The Mathematical Theory of Communication.” While copies of the original article are freely available on the internet, the more casual reader will appreciate the more recent edition from MIT Press which also includes a fabulous elucidative and extensive opening written by Warren Weaver. This paper contains the theoretical underpinning that allowed for the efflorescence of all modern digital communication to occur. It ranks as one of the most influential and far-reaching documents in human history rivaling even the Bible.

Further, my own excitement in Shannon stems in part from his Ph.D. thesis “An Algebra for Theoretical Genetics” (1940) which has inspired most of the theoretical material I’m always contemplating.

Google Doodle Art animated by artist Nate Swinehart celebrates Claude Shannon's 100th Birthday
Google Doodle Art animated by artist Nate Swinehart celebrates Claude Shannon’s 100th Birthday

Additional Sources:

For those looking for more information try some of the following (non-technical) sources:

Claude Elwood Shannon smoking

Some light poolside reading

Some light poolside reading.
At Home in the Universe: The Search for the Laws of Self-Organization and Complexity by Stuart Kauffman

Instagram filter used: Clarendon

Photo taken at:Gerrish Swim & Tennis Club

Introduction to Information Theory | SFI’s Complexity Explorer

Many readers often ask me for resources for delving into the basics of information theory. I hadn’t posted it before, but the Santa Fe Institute recently had an online course Introduction to Information Theory through their Complexity Explorer, which has some other excellent offerings. It included videos, fora, and other resources and was taught by the esteemed physicist and professor Seth Lloyd. There are a number of currently active students still learning and posting there.

Introduction to Information Theory

About the Tutorial:

This tutorial introduces fundamental concepts in information theory. Information theory has made considerable impact in complex systems, and has in part co-evolved with complexity science. Research areas ranging from ecology and biology to aerospace and information technology have all seen benefits from the growth of information theory.

In this tutorial, students will follow the development of information theory from bits to modern application in computing and communication. Along the way Seth Lloyd introduces valuable topics in information theory such as mutual information, boolean logic, channel capacity, and the natural relationship between information and entropy.

Lloyd coherently covers a substantial amount of material while limiting discussion of the mathematics involved. When formulas or derivations are considered, Lloyd describes the mathematics such that less advanced math students will find the tutorial accessible. Prerequisites for this tutorial are an understanding of logarithms, and at least a year of high-school algebra.

About the Instructor(s):

Professor Seth Lloyd is a principal investigator in the Research Laboratory of Electronics (RLE) at the Massachusetts Institute of Technology (MIT). He received his A.B. from Harvard College in 1982, the Certificate of Advanced Study in Mathematics (Part III) and an M. Phil. in Philosophy of Science from Cambridge University in 1983 and 1984 under a Marshall Fellowship, and a Ph.D. in Physics in 1988 from Rockefeller University under the supervision of Professor Heinz Pagels.

From 1988 to 1991, Professor Lloyd was a postdoctoral fellow in the High Energy Physics Department at the California Institute of Technology, where he worked with Professor Murray Gell-Mann on applications of information to quantum-mechanical systems. From 1991 to 1994, he was a postdoctoral fellow at Los Alamos National Laboratory, where he worked at the Center for Nonlinear Systems on quantum computation. In 1994, he joined the faculty of the Department of Mechanical Engineering at MIT. Since 1988, Professor Lloyd has also been an adjunct faculty member at the Sante Fe Institute.

Professor Lloyd has performed seminal work in the fields of quantum computation and quantum communications, including proposing the first technologically feasible design for a quantum computer, demonstrating the viability of quantum analog computation, proving quantum analogs of Shannon’s noisy channel theorem, and designing novel methods for quantum error correction and noise reduction.

Professor Lloyd is a member of the American Physical Society and the Amercian Society of Mechanical Engineers.

Tutorial Team:

Yoav Kallus is an Omidyar Fellow at the Santa Fe Institute. His research at the boundary of statistical physics and geometry looks at how and when simple interactions lead to the formation of complex order in materials and when preferred local order leads to system-wide disorder. Yoav holds a B.Sc. in physics from Rice University and a Ph.D. in physics from Cornell University. Before joining the Santa Fe Institute, Yoav was a postdoctoral fellow at the Princeton Center for Theoretical Science in Princeton University.

How to use Complexity Explorer: How to use Complexity Explore
Prerequisites: At least one year of high-school algebra
Like this tutorial? 


Syllabus

  1. Introduction
  2. Forms of Information
  3. Information and Probability
  4. Fundamental Formula of Information
  5. Computation and Logic: Information Processing
  6. Mutual Information
  7. Communication Capacity
  8. Shannon’s Coding Theorem
  9. The Manifold Things Information Measures
  10. Homework

Devourer of Encyclopedias: Stanislaw Lem’s “Summa Technologiae”

Read Devourer of Encyclopedias: Stanislaw Lem's "Summa Technologiae" (The Los Angeles Review of Books)
A review of Summa Technologiae by Stanislaw Lem by David Auerbach from the Los Angeles Review of Books.

Summa Technologiae

AT LAST WE have it in English. Summa Technologiae, originally published in Polish in 1964, is the cornerstone of Stanislaw Lem’s oeuvre, his consummate work of speculative nonfiction. Trained in medicine and biology, Lem synthesizes the current science of the day in ways far ahead of most science fiction of the time.

His subjects, among others, include:

  • Virtual reality
  • Artificial intelligence
  • Nanotechnology and biotechnology
  • Evolutionary biology and evolutionary psychology
  • Artificial life
  • Information theory
  • Entropy and thermodynamics
  • Complexity theory, probability, and chaos
  • Population and ecological catastrophe
  • The “singularity” and “transhumanism”

Source: Devourer of Encyclopedias: Stanislaw Lem’s “Summa Technologiae” – The Los Angeles Review of Books

I came across this book review quite serendipitously today via an Auerbach article in Slate, which I’ve bookmarked. I found a copy of the book and have added it to the top of my reading pile. As I’m currently reading an advance reader edition of Sean Carroll’s The Big Picture, I can only imagine how well the two may go together despite being written nearly 60 years apart.