🔖 Hayflick, his limit, and cellular ageing | Nature Reviews Molecular Cell Biology

Bookmarked Hayflick, his limit, and cellular ageing ( Nature Reviews Molecular Cell Biology)
Almost 40 years ago, Leonard Hayflick discovered that cultured normal human cells have limited capacity to divide, after which they become senescent ‚ÄĒ a phenomenon now known as the ‚ÄėHayflick limit‚Äô. Hayflick's findings were strongly challenged at the time, and continue to be questioned in a few circles, but his achievements have enabled others to make considerable progress towards understanding and manipulating the molecular mechanisms of ageing.
[1]
J. Shay and W. Wright, ‚ÄúHayflick, his limit, and cellular ageing.,‚ÄĚ Nat Rev Mol Cell Biol, vol. 1, no. 1, pp. 72‚Äď6, Oct. 2000. [PubMed]
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