🔖 Emerging Frontiers of Neuroengineering: A Network Science of Brain Connectivity

Emerging Frontiers of Neuroengineering: A Network Science of Brain Connectivity by Danielle S. Bassett, Ankit N. Khambhati, Scott T. Grafton (arxiv.org)
Neuroengineering is faced with unique challenges in repairing or replacing complex neural systems that are composed of many interacting parts. These interactions form intricate patterns over large spatiotemporal scales, and produce emergent behaviors that are difficult to predict from individual elements. Network science provides a particularly appropriate framework in which to study and intervene in such systems, by treating neural elements (cells, volumes) as nodes in a graph and neural interactions (synapses, white matter tracts) as edges in that graph. Here, we review the emerging discipline of network neuroscience, which uses and develops tools from graph theory to better understand and manipulate neural systems, from micro- to macroscales. We present examples of how human brain imaging data is being modeled with network analysis and underscore potential pitfalls. We then highlight current computational and theoretical frontiers, and emphasize their utility in informing diagnosis and monitoring, brain-machine interfaces, and brain stimulation. A flexible and rapidly evolving enterprise, network neuroscience provides a set of powerful approaches and fundamental insights critical to the neuroengineer's toolkit.

17 pages, 6 figures. Manuscript accepted to the journal Annual Review of Biomedical Engineering [1]


D. Bassett S., A. Khambhati N., and S. Grafton T., “Emerging Frontiers of Neuroengineering: A Network Science of Brain Connectivity,” arXiv, 23-Dec-2016. [Online]. Available: https://arxiv.org/abs/1612.08059. [Accessed: 03-Jan-2017]
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Author: Chris Aldrich

I'm a biomedical and electrical engineer with interests in information theory, complexity, evolution, genetics, signal processing, theoretical mathematics, and big history. I'm also a talent manager-producer-publisher in the entertainment industry with expertise in representation, distribution, finance, production, content delivery, and new media.

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