Information theory provides a constructive criterion for setting up probability distributions on the basis of partial knowledge, and leads to a type of statistical inference which is called the maximum-entropy estimate. It is the least biased estimate possible on the given information; i.e., it is maximally noncommittal with regard to missing information. If one considers statistical mechanics as a form of statistical inference rather than as a physical theory, it is found that the usual computational rules, starting with the determination of the partition function, are an immediate consequence of the maximum-entropy principle. In the resulting "subjective statistical mechanics," the usual rules are thus justified independently of any physical argument, and in particular independently of experimental verification; whether or not the results agree with experiment, they still represent the best estimates that could have been made on the basis of the information available.
It is concluded that statistical mechanics need not be regarded as a physical theory dependent for its validity on the truth of additional assumptions not contained in the laws of mechanics (such as ergodicity, metric transitivity, equal a priori probabilities, etc.). Furthermore, it is possible to maintain a sharp distinction between its physical and statistical aspects. The former consists only of the correct enumeration of the states of a system and their properties; the latter is a straightforward example of statistical inference.
DOI:https://doi.org/10.1103/PhysRev.106.620
On the Fallacy of Diminishing Returns
Nominated for quote of the week, which I encountered while reading Matt Ridley’s The Rational Optimist:
He who receives an idea from me, receives instruction himself without lessening mine; as he who lights his taper at mine, receives light without darkening me.
in a letter to Isaac McPherson
Darwin Library, Now Online, Reveals Mind of 19th-Century Naturalist | The Chronicle
A portion of Charles Darwin’s vast scientific library—including handwritten notes that the 19-century English naturalist scribbled in the margins of his books—has been digitized and is available online. Readers can now get a firsthand look into the mind of the man behind the theory of evolution.
The project to digitize Darwin’s extensive library, which includes 1,480 scientific books, was a joint effort with the University of Cambridge, the Darwin Manuscripts Project at the American Museum of Natural History, the Natural History Museum in Britain, and the Biodiversity Heritage Library.
The digital library, which includes 330 of the most heavily annotated books in the collection, is fully indexed—allowing readers to search through transcriptions of the naturalist’s handwritten notes that were compiled by the Darwin scholars Mario A. Di Gregorio and Nick Gill in 1990.
📅 18th International C. elegans Meeting, 22nd-26th June 2011
The Organizing Committee invites you to attend the 18th International C. elegans Meeting, sponsored by the Genetics Society of America. The meeting will be held June 22 – 26, 2011 at the University of California, Los Angeles campus. The meeting will begin on Wednesday evening, June 22 at 7:00 pm and will end on Sunday, June 26 at 12:00 noon. On Friday, June 24 at 5:00 pm there will be a Keynote Address by Joseph Culotti, Samuel Lunenfeld Research Institute, Toronto, Canada
Entropy Is Universal Rule of Language | Wired Science
The amount of information carried in the arrangement of words is the same across all languages, even languages that aren't related to each other. This consistency could hint at a single common ancestral language, or universal features of how human brains process speech. "It doesn't matter what language or style you take," said systems biologist…
Barnes & Noble Board Would Face Tough Choices in a Buyout Vote | Dealbook
If Leonard Riggio, Barnes & Noble's chairman, joins Liberty Media's proposed buyout of his company, the board needs to decide how to handle his 30 percent stake before shareholders vote on the deal.
The Science of Why We Don’t Believe Science | Mother Jones
How our brains fool us on climate, creationism, and the vaccine-autism link.
Bob Frankston on Communications
Computer pioneer who helped create the first spreadsheet, Bob Frankston, is this week's guest.
Phrase of the Week: “Disconfirmation Bias”
disconfirmation bias: n. The tendency to accept supportive evidence of a belief uncritically, but to actively refute or discount evidence that challenges that belief.
The Adventures of Sherlock Holmes
The Adventures of Sherlock Holmes
Sherlock Holmes, #3
mystery, detective
The Strand Magazine
1892
Kindle e-book
Amazon
Comprising the series of short stories that made the fortunes of the Strand, the magazine in which they were first published, this volume won even more popularity for Sherlock Holmes and Dr. Watson. Holmes is at the height of his powers in many of his most famous cases, including The Red-Headed League, The Speckled Band, and The Blue Carbuncle.
Read between January 02 – May 09, 2011
Quotes and Highlights:
You may remember the old Persian saying, ‘There is danger for him who taketh the tiger cub, and danger also for whoso snatches a delusion from a woman.’ There is as much sense in Hafiz as in Horace, and as much knowledge of the world.
Singularity is almost invariably a clue. The more featureless and commonplace a crime is, the more difficult it is to bring it home.
Well, moonshine is a brighter thing than fog, …
…as I said then, that a man should keep his little brain-attic stocked with all the furniture that he is likely to use, and the rest he can put away in the lumber-room of his library, where he can get it if he wants it.
“My God! It’s Watson,” said he. He was in a pitiable state of reaction, with every nerve in a twitter.
41% Note: An interesting early use of @Twitter…
I should be very much obliged if you would slip your revolver into your pocket. An Eley’s No. 2 is an excellent argument with gentlemen who can twist steel pokers into knots. That and a tooth-brush are, I think, all that we need.
magnifying lens.
87% First reference to Holmes with a magnifying lens in print that I’ve seen.Like
We describe the evolution of macromolecules as an information transmission process and apply tools from Shannon information theory to it. This allows us to isolate three independent, competing selective pressures that we term compression, transmission, and neutrality selection. The first two affect genome length: the pressure to conserve resources by compressing the code, and the pressure to acquire additional information that improves the channel, increasing the rate of information transmission into each offspring. Noisy transmission channels (replication with mutations) gives rise to a third pressure that acts on the actual encoding of information; it maximizes the fraction of mutations that are neutral with respect to the phenotype. This neutrality selection has important implications for the evolution of evolvability. We demonstrate each selective pressure in experiments with digital organisms.
To be published in J. theor. Biology 222 (2003) 477-483
DOI: 10.1016/S0022-5193(03)00062-6
Synthetic Biology’s Hunt for the Genetic Transistor | IEEE Spectrum
How genetic circuits will unlock the true potential of bioengineering

library opened on November 15, 1964, there were just over 1.1 million books on the shelves.